Publications (pre 2022)

  1. Monica E Neugebauer, Eli N Kissman, Jorge A Marchand, Jeff G Pelton, Nicholas A Sambold, Douglas C Miller, Michelle C Y Chang.
    "Conversion of a radical hydroxylase into a halogenase through reaction pathway engineering"
    Nature Chemical Biology (2021), in press.

  2. Jorge A Marchand , Merrick D Pierson Smela, Thomas H H Jordan, Kamesh Narasimhan, George M Church.
    "TBDB – A database of structurally annotated T-box riboswitch:tRNA pairs"
    Nucleic Acids Research (2020).

  3. Pei-Hsun Wu, Daniele M Gilkes, Jude M Phillip, Akshay Narkar, Thomas Wen-Tao Cheng, Jorge A Marchand, Meng-Horng Lee, Rong Li, Denis Wirtz
    "Single-cell morphology encodes metastatic potential"
    Science Advances (2019).

  4. Monica E Neugebauer, Kiera H Sumida, Jeffrey G Pelton, Jonathan L McMurry, Jorge A Marchand, Michelle CY Chang
    "A family of radical halogenases for the engineering of amino-acid-based products"
    Nature Chemical Biology (2019).

  5. Jorge A Marchand, Monica E Neugebauer, Madeleine C Ing, Chia-I Lin, Jeffrey G Pelton, Michelle CY Chang
    "Discovery of a pathway for terminal-alkyne amino acid biosynthesis"
    Nature (2019).

  6. Shyam B Khatau, Ryan J Bloom, Saumendra Bajpai, David Razafsky, Shu Zang, Anjil Giri, Pei-Hsun Wu, Jorge A Marchand, Alfredo Celedon, Christopher M Hale, Sean X Sun, Didier Hodzic, Denis Wirtz
    "The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration"
    Scientific Reports (2013).

Submitted & in preparation

  1. Jorge A Marchand , Kamesh Narasimhan, Thomas H H Jordan, Jon Aach, George M Church.
    "Installation of a parallel, orthogonal translation system"
    In preparation (2020).


  1. MCY Chang, JAM Benmaman, ME Neugebauer
    "Biosynthesis of bioorthogonal amino acids"
    US Patent App. 16/600,502 (2019).